With apologies to those who disagree...

I hate interleague play.

I hate what it does to the schedule.   The Yankees come to Oakland only once all year?? Come on!

I hate the "rivalries" it forces.  Sure, it's fun for NY and Chicago, but Colorado vs. Kansas City isn't setting anyone's hair on fire.

I hate the non-sequitur matchups that have to happen after the "natural rivalries" are done.  Gee, look, the Giants play the Blue Jays and Red Sox in June.  Hold me back.

I hate that it's that much less special to see the World Series matchup.  I used to enjoy seeing two teams that hadn't faced each other during the season.

(While i'm at it: I hate that the All-Star game counts for something.  I don't ever want to see an intentional walk during the All-Star game.  Thanks for making that possible, Mr. Selig.)

If you must have interleague play, then hold it only every third or fourth year.  Make it last for just two weekends -- each team plays the same opponent, once at home, once away -- and stick to the geographic rivalries; drop the idea of everybody playing everybody.

This would keep interleague play novel -- important because, IMHO, the novelty is a critical element to interleague play's popularity.  By allowing the idea to eat up so much of the schedule, MLB is killing that novelty and harming the rivalries that should be fostered. A's-Yankees comes to mind.

That would appease me, although it still wouldn't convince me.  I hate interleague play.